Complete Radiologic Response of Bulky Cerebral Metastases From Newly Diagnosed HER2-Positive Breast Cancer to Upfront Trastuzumab-Based Chemotherapy

نویسندگان

  • Daniel Brungs
  • Victor Sze
  • Louise Emmett
  • Richard J. Epstein
چکیده

The blood-brain barrier is traditionally regarded as an insurmountable obstacle to the effective drug therapy of brain metastases from solid tumors. Here we describe a striking case of complete radiologic response to chemotherapy, and propose that the critical success factors include the large tumor size, HER2-positivity, and concomitant use of trastuzumab.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2013